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	<title>Comments on: Understanding cancer through proteomics: Danny Hillis on TED.com</title>
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	<description>The TED Blog shares interesting news about TED, TEDTalks video, the TED Prize and more.</description>
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		<title>By: From Disney Imagineer to killing thousands of mice with cancer &#124; onemonkey.org</title>
		<link>http://blog.ted.com/2011/02/24/understanding-cancer-through-proteomics-danny-hillis-on-ted-com/comment-page-1/#comment-23954</link>
		<dc:creator><![CDATA[From Disney Imagineer to killing thousands of mice with cancer &#124; onemonkey.org]]></dc:creator>
		<pubDate>Sat, 24 Nov 2012 02:10:54 +0000</pubDate>
		<guid isPermaLink="false">http://blog.ted.com/?p=48302#comment-23954</guid>
		<description><![CDATA[[...] Understanding cancer through proteomics: Danny Hillis on TED.com [...]]]></description>
		<content:encoded><![CDATA[<p>[...] Understanding cancer through proteomics: Danny Hillis on TED.com [...]</p>
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		<title>By: Putuma Gqamana</title>
		<link>http://blog.ted.com/2011/02/24/understanding-cancer-through-proteomics-danny-hillis-on-ted-com/comment-page-1/#comment-13227</link>
		<dc:creator><![CDATA[Putuma Gqamana]]></dc:creator>
		<pubDate>Fri, 13 Apr 2012 09:21:07 +0000</pubDate>
		<guid isPermaLink="false">http://blog.ted.com/?p=48302#comment-13227</guid>
		<description><![CDATA[Correction: He says the differences in the isotopic features can be used as markers of disease. This is only correct if we could infer this from every isotopic feature uniquely, reproducibly and reliably. The example shown here is just peptide mass fingerprinting, which usually needs additional chemical validation like subsequent fragmentation, internal references, etc, in order to differentiate it from isobaric noise and contaminants. Hence, the inferrence of markers of disease from the differential isotopic features of the mass spectra is unfortunately not that straightforward...yet. Then there is the additional bioinformatic validation that usually takes place after the experiment is done, which is plagued by a myriad of its own problems. The good news however is that latest research now already shows that rigorous chemical, quantitative and bioinformatic verification can actually take place on the fly, i.e., during the experiment. So, we are a few months away from being able to routinely injecting the biological sample into the mass spectrometer, and spitting out the proteome, both global and differential, with little additional tinkering.]]></description>
		<content:encoded><![CDATA[<p>Correction: He says the differences in the isotopic features can be used as markers of disease. This is only correct if we could infer this from every isotopic feature uniquely, reproducibly and reliably. The example shown here is just peptide mass fingerprinting, which usually needs additional chemical validation like subsequent fragmentation, internal references, etc, in order to differentiate it from isobaric noise and contaminants. Hence, the inferrence of markers of disease from the differential isotopic features of the mass spectra is unfortunately not that straightforward&#8230;yet. Then there is the additional bioinformatic validation that usually takes place after the experiment is done, which is plagued by a myriad of its own problems. The good news however is that latest research now already shows that rigorous chemical, quantitative and bioinformatic verification can actually take place on the fly, i.e., during the experiment. So, we are a few months away from being able to routinely injecting the biological sample into the mass spectrometer, and spitting out the proteome, both global and differential, with little additional tinkering.</p>
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		<title>By: LINDA Scharf</title>
		<link>http://blog.ted.com/2011/02/24/understanding-cancer-through-proteomics-danny-hillis-on-ted-com/comment-page-1/#comment-10502</link>
		<dc:creator><![CDATA[LINDA Scharf]]></dc:creator>
		<pubDate>Mon, 02 Jan 2012 07:24:45 +0000</pubDate>
		<guid isPermaLink="false">http://blog.ted.com/?p=48302#comment-10502</guid>
		<description><![CDATA[Just to back-track on past comment- when assaulted with an antibiotic, bacteria will often become more slippery and travel to other areas of the body to attack- why tooth decay can lead to cardiac desease or prosthetic hip infection.]]></description>
		<content:encoded><![CDATA[<p>Just to back-track on past comment- when assaulted with an antibiotic, bacteria will often become more slippery and travel to other areas of the body to attack- why tooth decay can lead to cardiac desease or prosthetic hip infection.</p>
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		<title>By: LINDA Scharf</title>
		<link>http://blog.ted.com/2011/02/24/understanding-cancer-through-proteomics-danny-hillis-on-ted-com/comment-page-1/#comment-10501</link>
		<dc:creator><![CDATA[LINDA Scharf]]></dc:creator>
		<pubDate>Mon, 02 Jan 2012 07:20:30 +0000</pubDate>
		<guid isPermaLink="false">http://blog.ted.com/?p=48302#comment-10501</guid>
		<description><![CDATA[How interesting! I have been toying with the idea that antibiotics usually work by depriving the body of certain proteins which is fatal to the infection but not the human. Is the body forced to use alternate available proteins and thus function in an altered way which causes it to cancer? Does the increased &quot;slipperyness&quot; of the infective agent allow it to trigger this maladaptive response in the body? Hmmmm. I recently watched an interesting program about oragami folding in proteins, and the propensity of proteins to re-fold on the same &#039;crease-line&#039; of previous folds. Interesting new aproach to an evil desease.]]></description>
		<content:encoded><![CDATA[<p>How interesting! I have been toying with the idea that antibiotics usually work by depriving the body of certain proteins which is fatal to the infection but not the human. Is the body forced to use alternate available proteins and thus function in an altered way which causes it to cancer? Does the increased &#8220;slipperyness&#8221; of the infective agent allow it to trigger this maladaptive response in the body? Hmmmm. I recently watched an interesting program about oragami folding in proteins, and the propensity of proteins to re-fold on the same &#8216;crease-line&#8217; of previous folds. Interesting new aproach to an evil desease.</p>
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		<title>By: One year of TED picks. (4-4-11) &#171; Saliency</title>
		<link>http://blog.ted.com/2011/02/24/understanding-cancer-through-proteomics-danny-hillis-on-ted-com/comment-page-1/#comment-10432</link>
		<dc:creator><![CDATA[One year of TED picks. (4-4-11) &#171; Saliency]]></dc:creator>
		<pubDate>Fri, 23 Dec 2011 16:54:25 +0000</pubDate>
		<guid isPermaLink="false">http://blog.ted.com/?p=48302#comment-10432</guid>
		<description><![CDATA[[...] cancer through proteomic http://blog.ted.com/2011/02/24/understanding-cancer-through-proteomics-danny-hillis-on-ted-com/ Interesting intro to [...]]]></description>
		<content:encoded><![CDATA[<p>[...] cancer through proteomic <a href="http://blog.ted.com/2011/02/24/understanding-cancer-through-proteomics-danny-hillis-on-ted-com/" rel="nofollow">http://blog.ted.com/2011/02/24/understanding-cancer-through-proteomics-danny-hillis-on-ted-com/</a> Interesting intro to [...]</p>
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		<title>By: The costly war on cancer</title>
		<link>http://blog.ted.com/2011/02/24/understanding-cancer-through-proteomics-danny-hillis-on-ted-com/comment-page-1/#comment-7930</link>
		<dc:creator><![CDATA[The costly war on cancer]]></dc:creator>
		<pubDate>Wed, 01 Jun 2011 05:21:24 +0000</pubDate>
		<guid isPermaLink="false">http://blog.ted.com/?p=48302#comment-7930</guid>
		<description><![CDATA[[...] we are discussing cancer here are two interesting TED talks about it: TED Blog &#124; Understanding cancer through proteomics: Danny Hillis on TED.com William Li: Can we eat to starve cancer? &#124; Video on TED.com  The first discusses about how we are [...]]]></description>
		<content:encoded><![CDATA[<p>[...] we are discussing cancer here are two interesting TED talks about it: TED Blog | Understanding cancer through proteomics: Danny Hillis on TED.com William Li: Can we eat to starve cancer? | Video on TED.com  The first discusses about how we are [...]</p>
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		<title>By: El Servicio de Proteómica del CIPF participa en el consorcio español para el proyecto Proteoma Humano &#124; RDi Press</title>
		<link>http://blog.ted.com/2011/02/24/understanding-cancer-through-proteomics-danny-hillis-on-ted-com/comment-page-1/#comment-7121</link>
		<dc:creator><![CDATA[El Servicio de Proteómica del CIPF participa en el consorcio español para el proyecto Proteoma Humano &#124; RDi Press]]></dc:creator>
		<pubDate>Tue, 26 Apr 2011 19:36:45 +0000</pubDate>
		<guid isPermaLink="false">http://blog.ted.com/?p=48302#comment-7121</guid>
		<description><![CDATA[[...] Understanding cancer through proteomics: Danny Hillis on TED.com (ted.com) [...]]]></description>
		<content:encoded><![CDATA[<p>[...] Understanding cancer through proteomics: Danny Hillis on TED.com (ted.com) [...]</p>
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		<title>By: Jean Thomas</title>
		<link>http://blog.ted.com/2011/02/24/understanding-cancer-through-proteomics-danny-hillis-on-ted-com/comment-page-1/#comment-6225</link>
		<dc:creator><![CDATA[Jean Thomas]]></dc:creator>
		<pubDate>Wed, 16 Mar 2011 12:33:46 +0000</pubDate>
		<guid isPermaLink="false">http://blog.ted.com/?p=48302#comment-6225</guid>
		<description><![CDATA[Finally, I see some forward thinkers introducing a scientific way of treating a cancer(ing) patient holistically.  So much of the traditional treatment focuses on killing the cancer cells, whereas the holistic methods concentrate on strengthening the body&#039;s natural healing ability.  I can&#039;t wait until these approaches integrate the best that proteomics, genomics, nutrition, chemotherapy and radiation therapies have to offer.]]></description>
		<content:encoded><![CDATA[<p>Finally, I see some forward thinkers introducing a scientific way of treating a cancer(ing) patient holistically.  So much of the traditional treatment focuses on killing the cancer cells, whereas the holistic methods concentrate on strengthening the body&#8217;s natural healing ability.  I can&#8217;t wait until these approaches integrate the best that proteomics, genomics, nutrition, chemotherapy and radiation therapies have to offer.</p>
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		<title>By: Tweets that mention TED Blog &#124; Understanding cancer through proteomics: Danny Hillis on TED.com -- Topsy.com</title>
		<link>http://blog.ted.com/2011/02/24/understanding-cancer-through-proteomics-danny-hillis-on-ted-com/comment-page-1/#comment-5841</link>
		<dc:creator><![CDATA[Tweets that mention TED Blog &#124; Understanding cancer through proteomics: Danny Hillis on TED.com -- Topsy.com]]></dc:creator>
		<pubDate>Thu, 24 Feb 2011 18:03:37 +0000</pubDate>
		<guid isPermaLink="false">http://blog.ted.com/?p=48302#comment-5841</guid>
		<description><![CDATA[[...] This post was mentioned on Twitter by Andrew Davis and Chris Muscles, Venkat. Venkat said: Understanding cancer through proteomics: Danny Hillis on TED.com http://goo.gl/fb/MjINZ [...]]]></description>
		<content:encoded><![CDATA[<p>[...] This post was mentioned on Twitter by Andrew Davis and Chris Muscles, Venkat. Venkat said: Understanding cancer through proteomics: Danny Hillis on TED.com <a href="http://goo.gl/fb/MjINZ" rel="nofollow">http://goo.gl/fb/MjINZ</a> [...]</p>
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